In 2000 the AFI unveiled their 100 Years…100 Laughs list of the top 100 funniest movies in American cinema.
| # | Movie | Director | Year |
|---|---|---|---|
| 1. | Some Like It Hot | Billy Wilder | 1959 |
| 2. | Tootsie | Sydney Pollack | 1982 |
| 3. | Dr. Strangelove or: How I Learned to Stop Worrying and Love the Bomb |
Stanley Kubrick | 1964 |
| 4. | Annie Hall | Woody Allen | 1977 |
| 5. | Duck Soup | Leo McCarey | 1933 |
| 6. | Blazing Saddles | Mel Brooks | 1974 |
| 7. | MASH | Robert Altman | 1970 |
| 8. | It Happened One Night | Frank Capra | 1934 |
| 9. | The Graduate | Mike Nichols | 1967 |
| 10. | Airplane! | Jim Abrahams, David Zucker, Jerry Zucker | 1980 |
| 11. | The Producers | Mel Brooks | 1967 |
| 12. | A Night at the Opera | Sam Wood | 1935 |
| 13. | Young Frankenstein | Mel Brooks | 1974 |
| 14. | Bringing Up Baby | Howard Hawks | 1938 |
| 15. | The Philadelphia Story | George Cukor | 1940 |
| 16. | Singin’ in the Rain | Gene Kelly, Stanley Donen | 1952 |
| 17. | The Odd Couple | Gene Saks | 1968 |
| 18. | The General | Clyde Bruckman, Buster Keaton | 1927 |
| 19. | His Girl Friday | Howard Hawks | 1940 |
| 20. | The Apartment | Billy Wilder | 1960 |
| 21. | A Fish Called Wanda | Charles Crichton | 1988 |
| 22. | Adam’s Rib | George Cukor | 1949 |
| 23. | When Harry Met Sally… | Rob Reiner | 1989 |
| 24. | Born Yesterday | George Cukor | 1950 |
| 25. | The Gold Rush | Charlie Chaplin | 1925 |
| 26. | Being There | Hal Ashby | 1979 |
| 27. | There’s Something About Mary | Peter Farrelly, Robert Farrelly | 1998 |
| 28. | Ghostbusters | Ivan Reitman | 1984 |
| 29. | This Is Spinal Tap | Rob Reiner | 1984 |
| 30. | Arsenic and Old Lace | Frank Capra | 1944 |
| 31. | Raising Arizona | Joel Coen, Ethan Coen | 1987 |
| 32. | The Thin Man | W. S. Van Dyke | 1934 |
| 33. | Modern Times | Charlie Chaplin | 1936 |
| 34. | Groundhog Day | Harold Ramis | 1993 |
| 35. | Harvey | Henry Koster | 1950 |
| 36. | Animal House | John Landis | 1978 |
| 37. | The Great Dictator | Charlie Chaplin | 1940 |
| 38. | City Lights | Charlie Chaplin | 1931 |
| 39. | Sullivan’s Travels | Preston Sturges | 1941 |
| 40. | It’s a Mad, Mad, Mad, Mad World | Stanley Kramer | 1963 |
| 41. | Moonstruck | Norman Jewison | 1987 |
| 42. | Big | Penny Marshall | 1988 |
| 43. | American Graffiti | George Lucas | 1973 |
| 44. | My Man Godfrey | Gregory La Cava | 1936 |
| 45. | Harold and Maude | Hal Ashby | 1971 |
| 46. | Manhattan | Woody Allen | 1979 |
| 47. | Shampoo | Hal Ashby | 1975 |
| 48. | A Shot in the Dark | Blake Edwards | 1964 |
| 49. | To Be or Not to Be | Ernst Lubitsch | 1942 |
| 50. | Cat Ballou | Elliot Silverstein | 1965 |
| 51. | The Seven Year Itch | Billy Wilder | 1955 |
| 52. | Ninotchka | Ernst Lubitsch | 1939 |
| 53. | Arthur | Steve Gordon | 1981 |
| 54. | The Miracle of Morgan’s Creek | Preston Sturges | 1944 |
| 55. | The Lady Eve | Preston Sturges | 1941 |
| 56. | Abbott and Costello Meet Frankenstein | Charles Barton | 1948 |
| 57. | Diner | Barry Levinson | 1982 |
| 58. | It’s a Gift | Norman Z. McLeod | 1934 |
| 59. | A Day at the Races | Sam Wood | 1937 |
| 60. | Topper | Norman Z. McLeod | 1937 |
| 61. | What’s Up, Doc? | Peter Bogdanovich | 1972 |
| 62. | Sherlock Jr. | Buster Keaton | 1924 |
| 63. | Beverly Hills Cop | Martin Brest | 1984 |
| 64. | Broadcast News | James L. Brooks | 1987 |
| 65. | Horse Feathers | Norman Z. McLeod | 1932 |
| 66. | Take the Money and Run | Woody Allen | 1969 |
| 67. | Mrs. Doubtfire | Chris Columbus | 1993 |
| 68. | The Awful Truth | Leo McCarey | 1937 |
| 69. | Bananas | Woody Allen | 1971 |
| 70. | Mr. Deeds Goes to Town | Frank Capra | 1936 |
| 71. | Caddyshack | Harold Ramis | 1980 |
| 72. | Mr. Blandings Builds His Dream House | H. C. Potter | 1948 |
| 73. | Monkey Business | Norman Z. McLeod | 1931 |
| 74. | 9 to 5 | Colin Higgins | 1980 |
| 75. | She Done Him Wrong | Lowell Sherman | 1933 |
| 76. | Victor/Victoria | Blake Edwards | 1982 |
| 77. | The Palm Beach Story | Preston Sturges | 1942 |
| 78. | Road to Morocco | David Butler | 1942 |
| 79. | The Freshman | Fred C. Newmeyer, Sam Taylor | 1925 |
| 80. | Sleeper | Woody Allen | 1973 |
| 81. | The Navigator | Buster Keaton, Donald Crisp | 1924 |
| 82. | Private Benjamin | Howard Zieff | 1980 |
| 83. | Father of the Bride | Vincente Minnelli | 1950 |
| 84. | Lost in America | Albert Brooks | 1985 |
| 85. | Dinner at Eight | George Cukor | 1933 |
| 86. | City Slickers | Ron Underwood | 1991 |
| 87. | Fast Times at Ridgemont High | Amy Heckerling | 1982 |
| 88. | Beetlejuice | Tim Burton | 1988 |
| 89. | The Jerk | Carl Reiner | 1979 |
| 90. | Woman of the Year | George Stevens | 1942 |
| 91. | The Heartbreak Kid | Elaine May | 1972 |
| 92. | Ball of Fire | Howard Hawks | 1941 |
| 93. | Fargo | Joel Coen, Ethan Coen | 1996 |
| 94. | Auntie Mame | Morton DaCosta | 1958 |
| 95. | Silver Streak | Arthur Hiller | 1976 |
| 96. | Sons of the Desert | William A. Seiter | 1933 |
| 97. | Bull Durham | Ron Shelton | 1988 |
| 98. | The Court Jester | Melvin Frank, Norman Panama | 1956 |
| 99. | The Nutty Professor | Jerry Lewis | 1963 |
| 100. | Good Morning, Vietnam | Barry Levinson | 1987 |